- Lacks 1 double-p. plate (m3 or "Venarum et item arteriarum omnium integra absoluta que delineatio" but second unpaginated m3 present) and 1 full-p. ill. (leaf Q5, supplied in facsimilé); sm. tear in upper margin fold. plate; p.215-216 w. sm. dam. spot in text and just touching the sm. woodcut ill.; somewhat damp- and waterstained; occas. inner margins strengthened w. paper strip; upper hinge restored w. thin japanese; blank margins of woodcut title and portrait strengthened w. Japanese; library stamp on title (and later ms "21492" in lower blank margin) and recto portrait. Lacks ties.
= The editio princeps of the anotomical masterpiece by A. van Wesel or A. Vesalius. Adams V603; Durling 4577; Horblit 98; Cushing VI.A-1; Choulant p.45f; PMM 71: "The Fabrica, a handsomely printed folio, is remarkable for its series of magnificent plates, which set new technical standards of anatomical illustration, and indeed of book illustration in general. (...) Vesalius's was the most splendid and the most comprehensive of a large number of anatomical treatises of the sixteenth century. (...) No other work of the sixteenth century equals it, though many share its spirit of anatomical enquiry. It was translated, reissued, copies and plagiarized over and over again and its illustrations were used or copied in other medical works until the end of the eighteenth century". SEE ILLUSTRATION PLATE LVIII.